Neuronal and glial changes in the brain resulting from explosive blast in an experimental model

Table 1 Neuron densities number per mm³

Group		CA1	CA2-3	CA4	Dentate
Control	Mean	192.08	180.14	78.74	1535.7
n = 11	± SD	27.32	39.26	12.47	134.05
Single blast	Mean	181.08	174.97	76.44	1461.82
n = 16	± SD	26.53	36.46	14.47	98.03
Double blast	Mean	167.43	176.91	69.97	1467.26
n = 15	± SD	24.25	43.71	9.3	158.38
Triple blast	Mean	149.15	153.59	67.32	1560.9
n = 3	± SD	10.08	34.07	12.3	124.31
All blast	Mean	171.98	174.72	72.61	1473.48
All blast	± SD	26.08	39.62	12.45	132.57
Control vs single	p	ns	ns	ns	0.0092
Control vs Double	p	0.0005	ns	0.0126	0.0266
Control vs Triple	p	0.0013	ns	0.0802	ns
Control vs All	p	0.0004	ns	0.0385	ns
single vs Double	p	0.018	ns	0.07	ns
Single vs Triple	p	0.002	ns	0.13	ns
Double vs Triple	p	0.032	ns	ns	ns

The intergroup significance values are derived from the Mann-Whitney U-test, two tail. CA = neurons in the pyramidal layer of Cornu Ammonis (Ammon’s Horn) areas 1 to 4 of the hippocampus. Dentate = neuron densities in the dentate granule cell layer

ISSN: 2051-5960