Fig. 8

Correlation analysis of p-MAPT neuropathology in fornix and basal forebrain nuclei. Correlation analysis (Pearson Correlation Coefficient with Bonferroni probabilities) revealed a significant correlation between AT8-ir axons in the fornix and p-MAPT neuropathology in the nucleus basalis of Meynert (a; n = 30, R = 0.724, p < 0.002), septum (b; n = 36, R = 0.710, p < 0.003) and mammillary bodies (c; n = 37, R = 0.600, p < 0.03). No significant correlation was present between AT8-ir axons in the fornix and p-MAPT neuropathology in the nucleus accumbens (d; n = 37, R = 0.466, p = 0.328) or in the anterior thalamic nucleus (e; n = 37, R = 0.366, p = 1)