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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Hippocampal phospho-tau/MAPT neuropathology in the fornix in Alzheimer disease: an immunohistochemical autopsy study

Fig. 1

Phospho-MAPT neuropathology is present in the alveus in cases with hippocampal neurofibrillary degeneration. Left panels (original magnifications 10x): AT8 immunostaining in the hippocampal CA1 sector is demonstrated in representative cases with NIA/AA stages B0-1 (top-left), B2 (middle-left) or B3 (bottom-left) neurofibrillary degeneration. Right panels (original magnifications 200x): A case with B0-1 neurofibrillary degeneration demonstrated no axonal staining in the alveus (upper-right panel). Cases with B2 and B3 neurofibrillary degeneration (middle-right and lower-right panels, respectively) demonstrated punctate and wavy axonal AT8 staining in the alveus (arrowheads)

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