Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology

Table 2 Overview of the primary antibodies used in the present study to visualize UPR activation, GVD and pathological proteins

Antibody	Species	Dilution	Antigen	Source
pPERK	Rabbit	1:800	PERK phosphorylated at Thr981	Santa Cruz Biotechnology
pIRE1α	Rabbit	1:10.000	IRE1α phosphorylated at Ser724	Novus Biologicals
CK1δ	Mouse	1:25	Amino acids 296–355 of CK1δ	Santa Cruz Biotechnology
AT8	Mouse	1:800	Tau phosphorylated at Ser202 and Thr205	Pierce Biotechnology
IC16	Mouse	1:800	N-terminal amino acids 1–6 of Aβ	Kind gift of Prof. Dr. Korth, Heinrich Heine University, Düsseldorf, Germany [36]
3F4	Mouse	1:800	Amino acids 109–112 of protease sensitive and protease insensitive PrP	Covance

Primary antibodies used in the present study. The name of the primary antibody, the species of the host animal the primary antibody was raised in, the antigen recognized by the primary antibody and the source are listed

ISSN: 2051-5960