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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Amyloid-β 1–24 C-terminal truncated fragment promotes amyloid-β 1–42 aggregate formation in the healthy brain

Fig. 5

Bioinformatics analysis of Aβ42, Aβ24 and cross-aggregating regions and their stabilities. Regions and energies are predicted by Walsh’s PASTA 2.0 algorithm; lower energies indicate higher fibrillation propensity. a Self-aggregation propensities for the full length Aβ42 protein; b self-aggregation propensities for the Aβ24 fragment. c Cross-aggregation between the Aβ24 fragment and the C-terminal region (aa 25 to 42) of Aβ42

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