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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V)

Fig. 6

The connections of motor neuron-related area. The common lesion of the ALS patients who progressed to Stage V is emphasized. All the common lesions related to the motor neurons and pyramidal tract. Shaded areas: lesions that showed moderate or severe degeneration in all the patients regardless of the time for progression to Stage V to death or type of accumulated protein. Stippled areas: lesions that showed a different degree of degeneration depending on the time from progression to Stage V to death

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