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Table 1 Comparison of organ weights (expressed as percentage of body weight) in PS19 mice treated for 14 weeks with vehicle, weekly doses of 0.1 mg/kg dictyostatin, or biweekly doses of 0.3 mg/kg dictyostatin

From: Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy

 

Vehicle

Dicytostatin (0.3 mg/kg)

Dictyostatin (0.1 mg/kg)

Liver

5.34 +/−0.80

4.90 +/−0.56

5.36 +/−1.20

Spleen

0.28 +/−0.04

0.34 +/−0.07

0.29 +/−0.04

Kidney

1.79 +/−0.14

1.72 +/−0.16

1.65 +/−0.14

Heart

0.60 +/−0.05

0.58 +/−0.02

0.56 +/−0.03