From: Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy
Vehicle
Dicytostatin (0.3 mg/kg)
Dictyostatin (0.1 mg/kg)
Liver
5.34 +/−0.80
4.90 +/−0.56
5.36 +/−1.20
Spleen
0.28 +/−0.04
0.34 +/−0.07
0.29 +/−0.04
Kidney
1.79 +/−0.14
1.72 +/−0.16
1.65 +/−0.14
Heart
0.60 +/−0.05
0.58 +/−0.02
0.56 +/−0.03