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Table 1 Comparison of organ weights (expressed as percentage of body weight) in PS19 mice treated for 14 weeks with vehicle, weekly doses of 0.1 mg/kg dictyostatin, or biweekly doses of 0.3 mg/kg dictyostatin

From: Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy

  Vehicle Dicytostatin (0.3 mg/kg) Dictyostatin (0.1 mg/kg)
Liver 5.34 +/−0.80 4.90 +/−0.56 5.36 +/−1.20
Spleen 0.28 +/−0.04 0.34 +/−0.07 0.29 +/−0.04
Kidney 1.79 +/−0.14 1.72 +/−0.16 1.65 +/−0.14
Heart 0.60 +/−0.05 0.58 +/−0.02 0.56 +/−0.03