Fig. 4

Correlation of cytokine and chemokine levels in mouse and human acute infarcts, and infarcts at the stage of liquefactive necrosis. Data from Figs. 2 and 3 have been replotted to provide a direct comparison of cytokine and chemokine levels in acute mouse and human infarcts (a, b, and c), and human and mouse infarcts at the stage of liquefactive necrosis (d, e, and f). The specific cytokines and chemokines that are significantly different between each strain, and different between humans and each strain are provided in Table 4. The solid lines depict the correlation when all 25 cytokines and chemokines are taken into consideration for the calculation of the Pearson’s R values. The dotted lines depict the correlation when the cytokines and chemokines that are significantly different between species by a two-way ANOVA corrected for multiple comparisons are excluded from the calculation of the Pearson’s R values