Fig. 5
Expression level of inflammatory markers. RT-PCR was performed on the inflammatory markers a Il1ß (αSYNtg/tg G3Terc-/- mice vs. αSYNtg/tg; p = 0.0147), b TNFα and c TGFß. Inflammation-induced activation of monocytes was shown with CD14 (d), MHC2 (e) and CXCR1 (f). Monocyte activation was analyzed with CD80 (g) and Interferon γ induced protein CXCL10 (h). i Iba1 was clearly reduced in αSYNtg/tg G3Terc-/- mice (αSYNtg/tg G3Terc-/- mice vs. αSYNtg/tg; p = 0.0202). After substracting of the housekeeping gene all different groups were normalized to the average ct of the Terc+/+ group