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Fig. 9 | Acta Neuropathologica Communications

Fig. 9

From: Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes

Fig. 9

IHC analyses of brain sections of individuals with multiple system atrophy. Representative IHC staining of brain tissue sections from MSA patients. Images were taken from the pons or cerebellum. Arrows show GCIs. All of the antibodies stained inclusions, to some extent. EP1536Y showed the strongest staining. 4F8 stained only rare inclusions, but abundantly labeled axons (arrowheads). Antibodies 81A and LS4-2C3 also displayed strong reactivity to axons in the cerebellum. Antibodies LS4-2G12 and LS3-2C2 displayed weaker staining of inclusions in the cerebellum. Scale bar = 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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