From: Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD
Treatment | # rats | # of perivascular cuffs in RNFL (total/AQP4 loss) | # of perivascular cuffs in INL/OPL/ONL (total/with AQP4 loss) |
---|---|---|---|
T + NMO-IgGS | 5 | 5/0 | 3/1 |
T + NMO-IgGV | 4 | 8/0 | 12/8 |
T + NMO-IgG9 | 2 | 6/0 | n.d. |
T + co-IgG | 4 | 17/0 | 8/0 |