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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

Fig. 3

Kaplan-Meier analysis of progression free survival (PFS) and overall survival (OS) of molecular groups in Cohort 1. a. PFS of each molecular group (n = 734). Median PFS was 113.4 months for Group A, 66.5 months for Group B, 11.7 months for Group C, and 8.2 months for Group D (P < 0.0001, Log-rank test). Notably, Group D showed significantly shorter PFS than other groups (P < 0.0001, Log-rank test). b. OS of each molecular group (n = 758). Median OS was not reached for Groups A and B, 25.3 months for Group C, and 16.3 months for Group D (P < 0.0001, Log-rank test). Group D showed significantly shorter survival than any other groups (P < 0.0001, Log-rank test). Group A, IDH mutated- TERT mutated; Group B, IDH mutated-TERT wild-type; Group C, IDH wild-type-TERT wild-type; Group D, IDH mutated-TERT mutated

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Acta Neuropathologica Communications

ISSN: 2051-5960

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