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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

Fig. 1

Natural history of rotenone-induced retinal degeneration. a Schematic overview of the treatment regimens. b Real time in vivo assessment of RGC death by means of DARC reveals a peak in apoptotic cell counts at day 20 of the rotenone treatment scheme. c, d Representative DARC images of vehicle- (control) and rotenone-treated retinas at day 20. e-h Morphometric analysis of the thickness of the whole retina, NRFL, ONL, and photoreceptor IS/OS on OCT images indicates a time-dependent characteristic swelling and thinning of the retinal layers in rotenone- versus vehicle-treated rats

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Acta Neuropathologica Communications

ISSN: 2051-5960

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