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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system

Fig. 6

Recombinant IL-33 inhibits axon myelination in rat myelinating co-cultures. The cell cultures were treated with or without recombinant IL-33 from DIV 12 to 28, a and the cells immuno-labelled with SMI-31 and anti-MBP, markers for axons and mature myelin respectively. b Graph depicting the percentage of SMI-31+ cells in total field of view. c Graph depicting the percentage of myelination measured by MBP+ and SMI-31+ overlapping pixels/total SMI31 pixels. * P < 0.05. Data are presented as Mean + SEM, and were compiled from three independent experiments

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Acta Neuropathologica Communications

ISSN: 2051-5960

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