Skip to main content
Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency

Fig. 1

Serial axial T2 FLAIR MRI (a, c) and corresponding axial contrast-enhanced T1 MRI (b, d) imaging of patient during initial presentation and after three months of disease progression when biopsy was performed. a Initial MRI (Day 1 of hospitalization) shows cortical gray matter with increased T2 FLAIR signal that is most prominent in the right occipital lobe (arrow) and just appreciable in the left occipital lobe. The related sulci are prominent, not compressed. The juxta-cortical white matter appears normal. b There is prominent contrast enhancement of portions of the affected cortices with no leptomeningeal enhancement. c-d Surveillance axial T2 FLAIR MRI (c, Day 90 of hospitalization,) and contrast-enhanced T1 MRI (d, Day 82 of hospitalization,) show disease progression with prominent involvement of both occipital and both frontal lobes. e T2 MRI through the deep gray matter and brain stem (sagittal) on Day 81 of hospitalization demonstrates patchy regions with signal abnormality in the basal ganglia, thalami and brain stem, including the medial left thalamus, right lateral geniculate nucleus, inferior colliculus, interpeduncular nuclei, dorsal pontine nuclei, and lateral medullary nuclei

Back to article page