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Table 1 Functions of genes which show a significant correlation between DNA methylation and gene expression. The majority of genes were hypomethylated and up-regulated in pilocytic astrocytomas compared to diffuse astrocytomas, except the three genes highlighted in bold

From: DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

MAPK pathway and downstream targets:

DUSP5

FOS

MIR21

CDK6

Tumour suppressors:

AIM1

OPCML

MCC

IRX1

Multidrug resistance:

ABCC3

Inflammation:

SOCS3

IL6ST

CD59

Other:

FAM89A

FAM167A

PRSS23

WSCD1

STAMBPL1

TMEM169

Receptors and channels:

HRH1

LDLRAD3

RARRES1

IGF1R

GRIA4

CHRM3

TRPM8

KCND2

GJA1

Cell morphology, motility and interactions:

MDGA2

TM4SF1

TMEM132C

IGSF9B

KIRREL3

LEPREL1

TMEM49

COTL1

PTPRE