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Table 9 Up-regulation of chemoattractants and adhesion molecules for inflammatory cells in 0.05Pa or 0.05Pa + turbulent flow-loaded group

From: Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

3.0Pa < 0.05Pa
Symbol Gene Accession Start End Log Fold Change P-value Peaks
CX3CL1 ENST00000006053 57406348 57406458 3.20 2.9E-03 BOTTOM
CX3CL1 ENST00000563383 57406400 57406402 3.69 2.1E-02 TOP
VCAM1 ENST00000370119 101185296 101185298 4.89 1.7E-03 TOP
VCAM1 ENST00000370119 101185284 101185300 4.37 6.9E-06 BOTTOM
0.05Pa < 0.05Pa + turbulent flow
Symbol Gene Accession Start End Log Fold Change P-value Peaks
CCL2 ENST00000225831 32582302 32582304 2.27 2.4E-04 TOP
CCL2 ENST00000225831 32582222 32582386 2.06 1.2E-06 BOTTOM
CXCL1 ENST00000509101 74735046 74735111 1.45 1.2E-02 BOTTOM
CXCL6 ENST00000515050 74702302 74702396 1.87 2.6E-02 BOTTOM
ICAM1 ENST00000423829 10381756 10381818 1.39 7.5E-03 BOTTOM
ICAM2 ENST00000581417 62084077 62084249 1.38 5.5E-03 BOTTOM
SELE ENST00000367779 169703219 169703222 2.95 7.0E-03 BOTTOM
VCAM1 ENST00000370119 101185275 101185302 1.33 2.6E-02 BOTTOM
3.0Pa < 0.05Pa + turbulent flow
Symbol Gene Accession Start End Log Fold Change P-value Peaks
CCL2 ENST00000225831 32582302 32582304 2.08 2.6E-03 TOP
CCL2 ENST00000225831 32582222 32582386 1.94 4.4E-04 BOTTOM
CCL2 ENST00000225831 32582222 32582224 2.15 4.5E-02 TOP
CX3CL1 ENST00000563383 57406400 57406402 2.19 4.7E-04 TOP
CX3CL1 ENST00000006053 57406348 57406402 2.03 1.7E-04 BOTTOM
CXCL11 ENST00000306621 76957183 76957237 2.89 1.4E-02 TOP
CXCL6 ENST00000515050 74702302 74702396 2.11 1.6E-02 BOTTOM
SELE ENST00000367779 169703220 169703222 3.69 1.5E-02 TOP
SELE ENST00000367779 169703219 169703222 2.94 2.8E-03 BOTTOM
VCAM1 ENST00000370119 101185275 101185302 1.33 2.6E-02 BOTTOM