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Table 8 Over-represented pathways in 0.05Pa-loaded or 0.05Pa + turbulent flow-loaded group compared with 3.0Pa-loaded group

From: Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

Comparison

Peaks

REACTOME ID

Pathway

P-value

FDR

3.0Pa < 0.05Pa + TF

Top peaks

REACT_7970

Telomere Maintenance

7.53E-12

1.36E-10

  

REACT_8017

APC-Cdc20 mediated degradation of Nek2A

3.74E-03

2.32E-02

  

REACT_152

Cell Cycle, Mitotic

3.86E-03

2.32E-02

 

Bottom peaks

REACT_7970

Telomere Maintenance

2.67E-14

4.01E-13

  

REACT_152

Cell Cycle, Mitotic

8.97E-03

6.73E-02

3.0Pa < 0.05Pa

Top peaks

REACT_7970

Telomere Maintenance

5.21E-08

5.21E-07

  

REACT_383

DNA Replication

2.24E-02

1.12E-01

  

REACT_1538

Cell Cycle Checkpoints

8.86E-02

2.48E-01

  

REACT_6850

Cdc20:Phospho-APC/C mediated degradation of Cyclin A

1.20E-01

2.48E-01

  

REACT_152

Cell Cycle, Mitotic

1.35E-01

2.48E-01

  

REACT_8017

APC-Cdc20 mediated degradation of Nek2A

1.49E-01

2.48E-01

 

Bottom peaks

REACT_7970

Telomere Maintenance

1.16E-06

6.96E-06

  

REACT_152

Cell Cycle, Mitotic

1.03E-02

3.09E-02

  

REACT_383

DNA Replication

3.15E-02

6.30E-02

  1. FDR false discovery rate