Fig. 4

Altered tau and fyn expression at late stages of AD. Western blots of control and Alzheimer’s disease (AD) post-mortem human brain tissue probed with antibodies recognising (a) tau dephosphosphorylated at S199/S202 (Tau-1), b tau phosphorylated at S202 (CP13), c tau phosphorylated at S214, d tau phosphorylated at S262, and (e) tau phosphorylated at S306/S404 (PHF-1). Quantification of each epitope relative to total tau is shown on the right. Molecular weight markers (kDa) are shown on the left. Values represent mean ± SEM, n = 11–15 per group. Mann-Whitney non-parametric test, *p < 0.05, **p < 0.01, NS = not significant