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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis

Fig. 5

Expression of pro- and anti-inflammatory markers in DM patients. Cytokines driving Th1-, Th2- and Th17 pathways were analyzed in adult and juvenile patients. Expression levels of STAT1 and STAT2 were significantly increased in jDM patients, while STAT6 showed a significant increase in aDM muscle biopsies. Overall Th17-associated immune markers were expressed on a very low level. Data are represented as Box-Whiskers blot min-max with mean and standard deviation, level of significance p < 0.05; jDM n = 10; aDM n = 15; NC n = 10

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