Fig. 6From: C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriersInfluence of C9orf72-HRE risk haplotype on C9orf72 expression. Boxplots showing the association between the C9orf72-HRE risk haplotype and expression in tpm for C9orf72 S1 + S3a (a) and S1 + S3b (b) TSSs. Individuals carrying the risk haplotype in heterozygous and homozygous state have a higher expression value as compared to carriers of the non-risk haplotype. Boxplots (c) show quantitative comparison of C9orf72 transcript 3 in FTD-MAPT non-carrying the risk haplotype, heterozygotes and homozygotes for the risk haplotype. Expression values are expressed as NRQs valuesBack to article page