Fig. 5From: C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers C9orf72 reduction and C9orf72-AS increase in FTD brains. Quantitative comparisons of C9orf72 expression in frontal cortex of controls and FTD brains: reduction in the expression of C9orf72 total (a) and transcript 1 (b) is shown in C9orf72-HRE, FTD-GRN and FTD-MAPT mutation carriers. c Increase of C9orf72-AS3 in all FTD cases as compared to controls. Expression values are expressed as NRQs values, measurements are performed in triplicates and error bars reflect standard deviationsBack to article page