| Cases with chorea | Cases without chorea | ||||
---|---|---|---|---|---|---|
 | 1 | 2 | 3 | 4 | 5 | 6 |
Brain weight (g) | 800 | 1190 | 880 | 1140 | 940 | 1230 |
Cortical atrophy | F, T(base) | F(tip) | F&T(base) | F&T(base) | F,T(base) | T(tip) |
Frontal cortex | +++ | +++ | ++ | +++ | +++ | +++ |
Cingulate gyrus | +++ | +++ | +++ | +++ | +++ | +++ |
Temporal cortex | ++ | + | ++ | ++ | +++ | +++ |
Hippocampus | +++ | + | +++ | +++ | na | +++ |
Amygdala | +++ | + | na | +++ | +++ | +++ |
Caudate nucleus | +++ | +++ | +++ | +++ | +++ | +++ |
Putamen | +++ | + | +++ | ++ | +++ | +++ |
Globus pallidus | +++ | ± | ++ | ++ | ++ | ++ |
Thalamus | +++ | ± | ± | ++ | +++ | + |
Subthalamic nucleus | ± | ± | ± | ± | ± | ± |
Nucleus basalis of Meynert | + | - | ± | ± | ± | + |
Cerebellar dentate nucleus | ± | - | ± | ± | ± | + |
Red nucleus | ± | ± | ± | na | na | ± |
Substantia nigra | +++ | + | +++ | ++ | +++ | +++ |
Locus coeruleus | +++ | - | ± | ± | ++ | ++ |
Pontine nucleus | ± | ± | ± | ± | ± | ± |
Dorsal vagal nucleus | ± | ± | ± | na | ± | ± |
Hypoglossal nucleus | ± | - | ± | ± | ± | ± |
Inferior olivary nucleus | ± | ± | ± | ± | + | + |
Spinal cord | - | - | na | na | na | ± |