Table 1 Clinical, histological and molecular characteristics of our 6 patients with enchondromatosis who developed glioma
From: Characteristics of gliomas in patients with somatic IDH mosaicism
Age at glioma diagnosis (years) | Sex | Histology | IDH mutation | 1p19q co-deletion | ATRX loss of expression | Location | Multi-centric | History of chondrosarcoma | Survival (years) | |
|---|---|---|---|---|---|---|---|---|---|---|
Ollier disease | ||||||||||
1 | 28 | F | OAII | IDH1 R132H | No | Yes | T (n = 1), Fr (n = 1) | Yes | No | 2.5+ |
2 | 26 | M | - | - | - | - | Fr (n = 2) | Yes | Yes | 1+ |
3 | 30 | F | OII | IDH1 R132H | No | Yes | Fr (n = 1), T (n = 1) | Yes | No | 4 |
4 | 31 | M | GBM | IDH1 R132H | No | Yes | Fr (n = 2), P (n = 1) | Yes | No | 0.75 |
5 | 31 | F | OAIII | IDH1 R132H | No | Yes | Fr | No | Yes | 1.5+ |
Maffucci syndrome | ||||||||||
6 | 30 | M | OAII | IDH2 R132S | No | Yes | B | No | No | 3+ |