Fig. 2

Age at glioma in patients with enchondromatosis and sporadic IDH mutated gliomas according to grade and 1p/19q co-deletion. Y axis: age at glioma diagnosis (years). X axis: OD/MS: enchondromatosis patients with glioma, IDH: patients with sporadic IDH mutated gliomas without 1p/19q co-deletion, Codel: patients with sporadic IDH mutated gliomas with 1p/19q co-deletion. Median age at glioma diagnosis, was lower in OD/MS than in IDH patients (25.6 vs 41 years, p < 0.001) and in IDH than in Codel patients (41 years vs 50.8 years, p < 0.001). The difference remained significant when taking into account only LGG (OD/MS vs IDH patients: 26.9 vs 39 years, p < 0.001; IDH vs Codel patients: 39 vs 49 years, p = 0.01)