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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy

Fig. 1

Tau and amyloid pathology in MND Group 1 patients. Alzheimer-type tau pathology is present in CA1 region of hippocampus (a-c) and entorhinal cortex (d-f) in patient #35 with MND and Dementia with Lewy bodies as shown by immunostaining for tau with AT8 (a and d), pThr175 (b and e) and pThr217 (c and f) antibodies. Both diffuse (g) and cored (h) amyloid plaques are present with 4G8 antibody. Cerebral amyloid angiopathy affecting capillaries (i) is present in patient #33. Immunoperoxidase x400

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