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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions

Fig. 6

Soluble tau is hyperphosphorylated at 24 h. a Representative western blots for analysis of tau expression for total tau by DAKO and the phospho-tau by AT180. b i) Quantification using the sum of all fractions shows a significant increase in total AT180 at 24 h in OA injected mice when compared to DMSO injected controls. ii) The proportion of tau phosphorylated at AT180 is significantly increased by OA. No significant changes are observed in the insoluble, RIPA fraction (iii-iv). (n = 3, *p < 0.05)

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