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Table 2 The dopaminergic neuron density and the proportion of Lewy body-bearing neurons

From: High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction

Area

 

Density of dopaminergic neurons

Control

PD

PLAN

(n = 5)

(n = 7)

(n = 1)

Substantia nigra

LB harbouring neuron

0

1 (1)

6

total neuron

84 (14)

13 (6)

17

Locus coeruleus

LB harbouring neuron

0

1 (3)

17

total neuron

77 (13)

9 (10)

81

  1. TH tyrosine hydroxylase, Density of TH (+) neurons mean (SD) per mm2, control non-neurodegenerative disease, PD Parkinson disease, PLAN PLA2G6-associated neurodegeneration, LB Lewy body