From: Pneumococcal meningitis: Clinical-pathological correlations (meningene-path)
Scoring criteria | Scores | ||||
---|---|---|---|---|---|
Main category | Subcategory | 0 | 1 | 2 | 3 |
Meningeal infiltration | Absent | Focal mild infiltration | Multifocal mild or focal severe infiltration | Multifocal severe infiltration | |
Parenchymal damage | Parenchymal infiltration of inflammatory cells | Absent | Focal mild infiltration | Multifocal mild or focal severe infiltration | Multifocal severe infiltration |
Infarction | Absent | Focal small damage | Multifocal small or focal large inflammation | Multifocal large damages | |
Haemorrhage | |||||
Abscess | |||||
Vascular inflammation | Large meningeal artery inflammation | Absent | Focal mild (sub)endothelial infiltration/reactive changes | Multifocal mild (sub)endothelial infiltration/reactive changes or focal severe (sub)-endothelial infiltration with obstruction of vascular lumen and/or extension of infiltration in the media layer | Multifocal severe (sub)endothelial infiltration with obstruction of vascular lumen and/or extension of infiltration in the media layer |
Small parenchymal vessel inflammation | |||||
Thrombosis | Arterial thrombosis | Absent | Focal mild with partial obstruction of vascular lumen | Multifocal mild with partial obstruction of vascular lumen or focal severe with complete obstruction of vascular lumen and destruction of vessel wall | Multifocal severe with complete obstruction of vascular lumen and destruction of vessel wall |
Venous thrombosis | |||||
Small vessel thrombosis | |||||
Ventriculitis | Absent | A few inflammatory cells in the ventricle | Groups of inflammatory cells in the ventricle with/without ependymal infiltration | Extension of inflammatory cells into the periventricular tissue |