Table 3 Extracellular Aβ-pathology in transgenic AD mouse models. Aβ staining intensity: + weak staining, ++ moderate staining, +++ abundant staining, n.a not analyzed
Transgenic model | Age | Aβ37 | Aβ38 | Aβ39 | Aβ40 |
|---|---|---|---|---|---|
APP/PS1ΔEx9 | 9 m | + | ++ | + | +++ |
5XFAD | 7 m | +++ | +++ | +++ | +++ |
PDAPP | 18 m | + | + | + | ++ |
APP23 | 20 m | ++ | n.a. | ++ | +++ |
3xTg | 18 m | ++ | ++ | ++ | +++ |
APP/PS1KI | 10 m | +++ | +++ | +++ | +++ |