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Table 3 Extracellular Aβ-pathology in transgenic AD mouse models. Aβ staining intensity: + weak staining, ++ moderate staining, +++ abundant staining, n.a not analyzed

From: Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

Transgenic model Age Aβ37 Aβ38 Aβ39 Aβ40
APP/PS1ΔEx9 9 m + ++ + +++
5XFAD 7 m +++ +++ +++ +++
PDAPP 18 m + + + ++
APP23 20 m ++ n.a. ++ +++
3xTg 18 m ++ ++ ++ +++
APP/PS1KI 10 m +++ +++ +++ +++