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Table 2 Familial AD cases analyzed in the present study. Aβ staining intensity: - no staining; (+) barely detectable staining, + weak staining, ++ moderate staining, +++ abundant staining, n.a not analyzed, NP neuritic plaques

From: Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

     Aβ37 Aβ38 Aβ39 Aβ40 Aβ42
  Age Sex Mutation NP CAA NP CAA NP CAA NP CAA NP CAA
PS1-ΔEx9 61 m ΔExon9 ++ ++ + + - + ++ ++ +++ (+)
APP-I716F 47 m I716F ++ ++ + ++ - (+) ++ ++ +++ +
APP-Arctic 64 m E693Q ++ +++ + ++ + ++ +++ ++ +++ (+)
APP-Swe 61 f KM670/671NL + ++ - ++ - + n.a. n.a. +++ (+)