Table 2 Familial AD cases analyzed in the present study. Aβ staining intensity: - no staining; (+) barely detectable staining, + weak staining, ++ moderate staining, +++ abundant staining, n.a not analyzed, NP neuritic plaques
Aβ37 | Aβ38 | Aβ39 | Aβ40 | Aβ42 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age | Sex | Mutation | NP | CAA | NP | CAA | NP | CAA | NP | CAA | NP | CAA | |
PS1-ΔEx9 | 61 | m | ΔExon9 | ++ | ++ | + | + | - | + | ++ | ++ | +++ | (+) |
APP-I716F | 47 | m | I716F | ++ | ++ | + | ++ | - | (+) | ++ | ++ | +++ | + |
APP-Arctic | 64 | m | E693Q | ++ | +++ | + | ++ | + | ++ | +++ | ++ | +++ | (+) |
APP-Swe | 61 | f | KM670/671NL | + | ++ | - | ++ | - | + | n.a. | n.a. | +++ | (+) |