Skip to main content

Table 1 Clinical and pathological data of sporadic AD cases and non-demented controls. Aβ staining intensity: - no staining; (+) barely detectable staining, + weak staining, ++ moderate staining, +++ abundant staining; NP neuritic plaques

From: Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

       4G8 Aβ37 Aβ38 Aβ39 Aβ40
No. Age Sex Braak Diagnosis ApoE NP CAA NP CAA NP CAA NP CAA NP CAA
#1 92 M IV AD 3/3 ++ + - - - + - + + +
#2 92 F IV AD 3/3 + ++ - - - + - - + +
#3 93 M IV AD 3/3 + +++ - +++ - ++ - ++ ++ +++
#4 91 M IV AD 4/2 ++ +++ - + - + - - ++ +++
#5 84 F IV AD 4/3 ++ + - + - ++ - ++ + ++
#6 91 F IV AD 4/3 ++ ++ - ++ (+) + - + ++ +++
#7 88 F IV AD 3/3 + + - - - - - - + +
#8 92 F IV AD 4/2 ++ ++ - + (+) + - + + ++
#9 79 F IV AD 4/3 ++ +++ (+) ++ (+) +++ - ++ ++ +++
#10 84 F IV AD 3/2 ++ - - - - - - - + -
#11 91 F IV AD 4/3 ++ + - (+) - - - (+) (+) +
#12 86 M IV AD 3/3 + ++ - +++ - ++ - +++ + ++
#13 88 F IV AD 3/3 ++ + - - - - - - - +
#14 96 F V AD + CAA 4/3 ++ +++ - + - +++ - ++ ++ +++
#15 82 F V AD + CAA 3/3 ++ +++ - ++ - +++ + +++ +++ +++
#16 61 F VI DS 3/3 ++ - - - - - - - + -
#17 58 M VI DS 4/3 ++ ++ (+) + + + - - ++ ++
#18 64 F V DS 3/3 ++ ++ - ++ - ++ - ++ ++ ++
#19 91 M I NDC 3/3 - - - - - - - - - -
#20 78 F I NDC 3/3 (+) - - - - - - - - +
#21 73 M 0 NDC 3/3 - - - - - - - - - -
#22 84 M I NDC 3/3 - - - - - - - - - -
#23 88 F I NDC 3/3 + - - - - - - - - -
#24 78 M I NDC 4/3 ++ + - - - + - - + ++
#25 82 F I NDC 3/3 - - - - - - - - - -
#26 70 M 0 NDC 3/2 - - - - - - - - - -