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Table 1 Human brain samples

From: Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy

Case no

Age at death (years)

Gender (M/F)

Age at onset (years)

PMI (hours/days)

Brain weight (g)

Analysis

Ctrl_1

70

M

-

18 h

1482

IHC, IF

Ctrl_2

64

F

-

5 h

1204

IHC, IF, PLA, WB

Ctrl_3

84

F

-

96 h

1210

IHC, IF, PLA

Ctrl_4

59

M

-

na

1390

IHC, IF, PLA

Ctrl_5

82

F

-

9 h

1200

WB

Ctrl_6

80

M

-

16 h

1200

WB

APPswe_1

62

M

53

40 h

1024

IHC, IF, PLA, WB

APPswe_2

66

M

61

24 h

1140

IHC, IF, PLA, WB

APPswe_3

56

M

44

24 h

1161

IHC, IF, PLA, WB

CBD_1

80

F

74

8 days

1075

IHC, IF, PLA, WB

CBD_2

69

M

62

66 h

~1000

IHC, IF, PLA

CBD_3

70

M

64

24 h

930

IHC, IF, PLA

CBD_4

67

F

59

48 h

1045

WB

PSP_1

66

F

59

144 h

1490

IHC, IF, PLA

PSP_2

71

F

63

na

1121

IHC, IF, PLA

PSP_3

68

M

<66

na

1350

IHC, IF, PLA

  1. PMI post-mortem interval, time from death until autopsy, IHC immunohistochemistry, IF immunofluorescence, PLA proximity ligation assay, WB western blot, na not available