Fig. 5

APP/PSEN1 and Sorcs1 -/- x APP/PSEN1 mice display vascular Aβ within the brain. Aβ was detectible within cerebral blood vessels of male and female APP/PSEN1 and Sorcs1 -/- x APP/PSEN1 mice (n = 2–3/group) when assessed via immunohistochemistry using 6E10 and collagen IV. Data expressed as mean ± s.e.m. Scale bar = 200 μm