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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: New insights into the protein aggregation pathology in myotilinopathy by combined proteomic and immunolocalization analyses

Fig. 6

Immunolocalization of Z-disc (−associated) proteins II. Double immunofluorescence staining was performed on serial skeletal muscle cryosections from a myotilinopathy patient (ID1 in Table 1) using antibodies directed against myopalladin, desmin, plectin, nestin, and syncoilin and either filamin C or myotilin. Nuclei were visualized by the blue-fluorescent DAPI nucleic acid stain. Data of semiquantitative assessment of immunofluorescence intensities in abnormal areas A1–A3 are listed in Table 3. Scale bar = 50 μm

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