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Table 1 Demographic and biomarker information for subjects from Emory and ADNI

From: CSF complement 3 and factor H are staging biomarkers in Alzheimer’s disease

  ADNI Emory
  MCI (n = 135) AD (n = 95) MCI (n = 51) AD (n = 22)
Male (%) 86 (64 %) 53 (56 %) 28 (55 %) 6 (27 %)
Age (S.D.), yr 74.7 (7.6) 74.3 (7.7) 69.0 (7.4) 65.6 (8.8)
Education (S.D.), yr 15.8 (2.9) 14.9 (3.1) 15.4 (2.5) 13.9 (2.4)
Having at least one APOE4 allele 86 (64 %) 67 (70 %) 25 (49 %) 8 (36 %)
CSF     
Aβ42 (pg/mL) 136.7 (31.4) 143.5 (39.9) 129.8 (55.3) 168.3 (104.0)
t-Tau (pg/mL) 122.8 (60.6) 122.5 (57.8) 97.7 (49.6) 120.3 (60.0)
p-Tau181 (pg/mL) 42.4 (16.1) 41.4 (19.9) 55.6 (25.7) 61.1 (26.2)
FH (pg/mL) 1568 (629) 1750 (835) 1594 (493) 1692 (474)
Z-score, log(C3) −0.060 (0.929) 0.061 (1.084) −0.481 (1.031) −0.064 (0.784)
  1. MCI: mild cognitive impairment with CSF t-Tau/Aβ42 ≥ 0.39; AD: mild dementia due to Alzheimer's disease