Fig. 4

Age and gender are major factors determining lipid composition in lumbar spinal cords in G93A mice. Partial-least square discriminant analyses a show that age is the major factor explaining differences in fatty acid composition between G93A samples. Univariate analyses b show age- and gender-related changes in the amount of docosahexaenoic and arachidonic fatty acids. ^abc indicate significant effects (p < 0.01) of age, gender, and their interaction, respectively, after 2 way ANOVA. * shows significant differences for Bonferroni post-hoc analyses (*p < 0.05, **p < 0.01, ****p < 0.0001) between genders at a given age