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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS

Fig. 1

Gender influences weight changes associated to disease onset and progression (a, b), stride length (c), clinical progression (d), and survival (e) in hSOD-G93A mice. Weight evolution across age in hSOD-G93A mice a with arrows indicating calculated maximum weight. Bars in b are means ± SEM of the age at maximum weight or time spent for a 10 % loss from maximum weight, expressed in days. Bars in c are means ± SEM of the age of clinical onset measured by stride length analysis, expressed in days. Dots in d shows disease duration among the G93A colony, separated by gender, expressed in days. e shows the survival curve. In a abc indicate, significant effects (p < 0.01) of age, gender and their interaction, respectively, after 2 way ANOVA. * indicates p < 0.05 between male and female mice of the same age with Student’s t test. **, p < 0.01 after a Kaplan-Meyer analysis

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