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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter

Fig. 6

Expression pattern of the small HSP in cortical MS lesions. Grey matter from non-neurological cases and NAGM, intracortical demyelination and subpial lesions from MS cases were double labelled with HLA-DR (pink) and the small HSPs (brown), HSPB1 (a), HSPB6 (b), HSPB8 (c) or HSPB11 (d). Quantification revealed no correlation between the expression pattern of the small HSPs and cortical damage (A5, B5, C5, D5). NAGM was compared versus the control, intracortical and subpial groups by the use of Mann-Whitney U test. Scale bar = 25 μm. CON = control, NAGM = normal appearing grey matter, IC = intracortical, SP = subpial

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