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Table 4 Tumor grade is correlated with mutational load within histological subtypes of diffuse glioma

From: PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

 

Grade II

Grade III

Grade IV

P

Oligodendroglioma

21.8 ± 10.3 (65)

28.1 ± 13.5 (45)

 

0.011

Astrocytoma

18.8 ± 13.1 (30)

36.8 ± 47.6 (68)

 

0.0050

Oligoastrocytoma

20 ± 9 (42)

29.3 ± 14.3 (31)

 

0.0025

GBM

  

57.3 ± 19.9 (261)

 
  1. Values are listed as the average number of non-silent mutations +/− SD (number of tumors analyzed. P values were calculated using an anova