Table 4 Immunohistochemical and molecular characteristics of PGNT cases
SLC44A1-PRKCA (FISH) | KIAA1549-BRAF (RT-PCR) | BRAF mutation (IHC and/or sequencing) | FGFR1 mutation (sequencing) | Phospho-ERK (IHC and/or WB) | H3.3 mutation (IHC) | p53 accumulation (IHC) | |
|---|---|---|---|---|---|---|---|
case 1 | + | - | - | - | + | - | - |
case 2 | + | - | - | - | + | - | - |
case 3 | + | - | - | - | + | - | - |
case 4 | + | ND | - | - | + | - | - |