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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions

Fig. 1

HK2 and PK expression in MS lesions. HK2 and PK are weakly expressed throughout the NAWM (a, d). Expression of both HK2 and PK was more pronounced in active and inactive MS lesions (b-c, e-f). Insets show immunofluorescence labelling of GFAP (red) and HK2 (green, b-c) or PK (green, e-f) indicating that astrocytes in MS lesions express high levels of HK2 and PK. Staining intensity of HK2 and PK2 in MS lesions was increased as compared to NAWM in the same section (g). +/− = similar staining intensity as compared to NAWM, + = increased staining intensity as compared to NAWM, ++ = strongly increased staining intensity as compared to NAWM

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