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Table 1 Age, sex and immunohistochemical results for Aβ42 and hyperphosphorylated tau in cats

From: The domestic cat as a natural animal model of Alzheimer’s disease

No. Age Sex Aβ42 HP-tau
1 fetus (50 days) F +a
2 fetus (50 days) M +a
3 2-week-old F
4 2-week-old F
5 3-year-old M
6 3-year-old M
7 4-year-old F
8 4-year-old F
9 5-year-old F
10 8-year-old F +
11 14-year-old F
12 14-year-old M + ++
13 15-year-old F + +
14 15-year-old M +
15 15-year-old ND +
16 16-year-old F +
17 16-year-old M +
18 17-year-old F +
19 17-year-old F + +
20 17-year-old ND + +
21 18-year-old F + +
22 19-year-old F + ++
23 20-year-old F + +
24 20-year-old ND + ++
25 22-year-old M + +
  1. Aβ42: -, negative; +, small aggregates of Aβ42 were observed in the parietal and temporal cortices on FA-pretreated sections, and intracellular aggregates of Aβ 42 were observed in the cytoplasm of hippocampal pyramidal cells. HP-tau: -, negative; +, AT8-positive cells limited to the entorhinal cortex; ++, AT8-positive cells in the entorhinal cortex and throughout the hippocampus. F, female; M; male, ND, no data; a, weak AT8 positivity on the surface of cerebral cortex