Fig. 10

Double-labelling immunofluorescence and confocal microscopy in the substantia nigra in PD cases stages 4 and 5 to α-synuclein (b, e, h, k, n, q) and p54 (a), eIF3 (d), GRP78 (g), GRP94 (j), IRE1 (m), and XBP1 (p); c, f, i, l, o, r: merge. α-synuclein in Lewy bodies and neurites (red) only co-localizes with eIF3 (green). Paraffin sections, nuclei are stained with DRAQ5^TM. a-f, bar = 35 μm; G-I, m-o, bar = 30 μm; j-l, p-r, bar = 20 μm