Fig. 5

Immunohistochemistry for CSPα and synaptophysin in the cerebral cortex of an early stage AD-ANCL patient (a) DNAJC5/CSPα immunohistochemistry in the cerebral cortex of an early stage AD-ANCL patient (zone of staining above arrowhead); the underlying white matter is unstained. b non-mutation control subject. c Immunohistochemistry for synaptophysin in the cerebral cortex of an early stage AD-ANCL patient (zone of staining above arrowhead); the underlying white matter is unstained. d non-mutation control subject. Bar: 500 μm. f Quantification of the intensity of immunoreactivity staining (luminance measured as arbitrary values) (graph). Values represent the mean ± S.E.M. of three independent experiments using Student’s t test