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Table 2 Summary of intrastriatal injections into Tg(SNCA)1Nbm/J mice

From: Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein

Number of mice injected Injected materiala Time post-injection when the animal was euthanized (months) Spread of pathology
4 30 μl PBS 3 No
4 30 μl PBS 6 No
4 30 μl PBS 9 No
4 30 μl MSA1 BE 3 No
4 30 μl MSA1 BE 6 Yes
4 30 μl MSA1 BE 9 Yes
4 30 μl MSA2 BE 3 No
4 30 μl MSA2 BE 6 Yes
4 30 μl MSA2 BE 9 Yes
4 30 μl iLBD1 BE 3 No
4 30 μl iLBD1 BE 6 Yes
4 30 μl iLBD1 BE 9 Yes
4 30 μl iLBD2 BE 3 No
4 30 μl iLBD2 BE 6 Yes
4 30 μl iLBD2 BE 9 Yes
  1. PBS phosphate-buffered saline, BE brain extract, MSA multiple system atrophy, iLBD incidental Lewy body disease