From: Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits
Aβ | Human | Mouse | ||||
---|---|---|---|---|---|---|
Transgenes | PrP.HuAβ/PS1 | PrP.HuAβ | PrP.MoAβ/PS1 | |||
Line | 85 | 57 | C3.3xS9 | Q2.2xS9 | MHSI-695 | D-943 |
Age (mo)* | 16 | 21 | 18 | 22 | 20 | 24 |
Hippocampus | +++ | +++ | +++ | +++ | +++ | ++ |
Cerebellum | +++ | +++ | + | - | + | ++ |