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Table 1 Comparison of the frequency of cerebellar amyloid deposits among the different lines of transgenic mice analyzed

From: Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits

Human

Mouse

Transgenes

PrP.HuAβ/PS1

PrP.HuAβ

PrP.MoAβ/PS1

Line

85

57

C3.3xS9

Q2.2xS9

MHSI-695

D-943

Age (mo)*

16

21

18

22

20

24

Hippocampus

+++

+++

+++

+++

+++

++

Cerebellum

+++

+++

+

-

+

++

  1. +: 1–5 plaques, ++: 6–20 plaques, +++: >20 plaques
  2. *Age analyzed