Fig. 6

The microsomal fraction of C99 A2T was incubated and subjected to Western Blotting analysis (a). Aβ production from the microsomal fraction of C99 A2T cells was significantly reduced compared with that detected in C99 WT cells. Aβ production was determined by subtracting the amount of Aβ at 0 min from that at 20 min. Data represent means ± SD of four independent experiments (b). NS, not significant. **P < 0.005 (unpaired t-test)