Skip to main content

Advertisement

Table 1 Material after application of exclusion and inclusion criteria

From: Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2-q13 duplications

Group Case # Sex Age (y) Cause of death PMI (h) Hem Brain weight (g)
Dup(15) AN14762 M 9 SUDEP 13.6 R 1,130
autism AN06365 M 10 SUDEP 17.7 R 1,070
AN09402 M 11 SUDEP 10.5 R 1,540
AN07740 F 15 SUDEP (suspected) 24.0 L 1,141
AN09470 F 15 Pneumonia L 1,125
AN07993 F 22 SUDEP 11.8 L 1,209
AN05983 M 24 SUDEP 36.3 L 1,200
AN14829 F 26 SUDEP (suspected) 28.6 R 1,310
Mean ± SD 16 ± 7   20.3 ± 9.6   1,215 ± 149
Idiopathic autism HSB4640 M 8 Asthma attack 13.8 R 1,740
AN01293 M 9 SUDC 3.7 R 1,690
AN02736 M 15 Pneumonia 2.5 L 1,390
AN01570 F 18 SUDEP 6.7 L 2,100
IBR93-01 M 23 Seizure-related 14.0 L 1,610
AN08166 M 28 Seizure-related 43.0 R 1,580
NP06-54 M 32 Glioblastomaa L 1,260
AN06420 M 39 Heart failure 13.9 R 1,520
Mean ± SD 21 ± 11   14.0 ± 13.7   1,611 ± 251
Control UMB1706 F 8 Cardiac transplant rejection 20.0 R 1,340
UMB1670 M 14 Asphyxia (hanging) 5.0 R 1,420
UMB4722 M 14 Traumatic injuries 16.0 R 1,340
BTB-3960 F 25 Not established 26.0 L 1,520
UMB4637 F 31 Traumatic injuries 17.0 L 1,354
IBR291-00 M 32 Heart failure 14.0 R 1,401
IBR212-98 F 33 Bronchopneumonia 6.0 L 1,260
Mean ± SD 22 ± 10   14.9 ± 7.4   1,376 ± 81
  1. PMI post-mortem interval, Dup(15) chromosome 15q11.2-13.1 duplication syndrome, SUDEP sudden unexpected death in epilepsy, SUDC sudden unexplained death in childhood. Glioblastomaa was found as a single lesion located in the inferior temporal gyrus of the right hemisphere. Neoplastic changes were not detected in the left hemisphere examined morphometrically