Fig. 4
From: Cortical tau load is associated with white matter hyperintensities
Correlations between total white matter sclerotic index (a) (WM SI; measure of small vessel disease severity) as well as total cortical percentage area covered by HPτ-IR (b) (AT8 antibody for hyperphosphorylated tau burden) and 4G8 (c) immunoreactivity (Aβ-IR; for amyloid-β depositions/plaques) with age related white matter change score (ARWMC; measure for white matter hyperintensities) in cases with minimal hyperphosphorylated tau pathology (classified as Braak NFT stage 0-II [6]). Only total WM SI (a) correlated with total ARWMC score; no correlation was seen between total cortical HPτ-IR and Aβ-IR with total ARWMC scores. Only significant p values (and associated correlation coefficients (ρ)) are shown